Terahertz waves are a type of electromagnetic wave between microwaves and infrared waves. Due to its physical properties such as strong penetration, non-ionization and strong absorption, and the ability to achieve non-contact regulation of synaptic transmission, it has shown great application prospects. The synaptic transmission process is closely related to neurodegenerative diseases. Understanding the response of terahertz waves to the synaptic transmission process has a guiding role in the prevention and treatment of related diseases. This paper first introduces the physical properties of terahertz waves, biological effects and related concepts of synaptic transmission in detail, and then focuses on the influence of terahertz waves on the synaptic transmission process, namely the presynaptic, synaptic cleft and postsynaptic stages. Finally, the potential application of terahertz waves in the future synaptic transmission process is summarized and prospected.